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CAPriCORN Site Lead Co-Authors Report Published in JAMA Cardiology on Rationale and Design Features of the ADAPTABLE Trial

The Journal of the American Medical Association (JAMA) Cardiology recently published a report that details the intricate design elements of the Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness (ADAPTABLE) trial.  Among the authors of the report is CAPriCORN’s Northwestern Medicine Site Lead and Assistant Professor of Medicine (Cardiology) and Preventive Medicine (Health and Biomedical Informatics) Faraz Ahmad, MD, MS.

The paper aims to inspire further efforts to improve efficiency and patient-centricity in future clinical research and explains some of the advantages of conducting a study within the vast National Patient Centered Clinical Research Network (PCORnet).

“As the first randomized trial executed within the PCORnet data infrastructure, the ADAPTABLE trial represents, to our knowledge, the first large-scale, EHR-enabled clinical trial executed within the US and uses several innovative and transformational operational patient-centered approaches previously untested in cardiovascular outcomes trials,” writes the study authors in the paper introduction.

Of the 40 PCORnet sites that participated in the trial, 3 were CAPriCORN network sites, including Northwestern University, The University of Chicago, and Rush University. Pastors4PCOR and Sinai Urban Health also collaborated with CAPriCORN on the ADAPTABLE trial.

To read the full report, visit the JAMA Cardiology website.

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